CEO Evelyn foresees her adopted daughter Chloe murdering her. After a hurricane traps them on Terror Island, she reunites with her biological daughter Maya and builds defenses against a prehistoric python. Chloe and Sterling ignore warnings, triggering a massacre; Chloe is swallowed but fuses with the snake. Six months later, as Claire, she returns as a 40-meter titan python. Evelyn and Maya fight back in the sinkhole, sever her tail, and send her into lava. The island sinks, and they build a global ecological defense network.